The growing popularity of decentralized clinical trials raises the need to secure sensitive data collected within particular research programs. Its organizer must produce a cyber security plan in advance in the event of hacking attacks. Critical areas include the issues of data protection, incident response methods, and personnel training in cybersecurity policies and procedures. The cornerstone of cybersecurity efforts is adequate software, data encryption, backup, and secure authentication. Updating all security measures and keeping track of innovations are other essential aspects.